2. Radiation Interactions

Understanding how radiation interacts with matter is fundamental to imaging physics and radiation protection.

Learning Objectives

  • Describe the photoelectric effect and its clinical significance
  • Explain Compton scattering and its impact on image quality
  • Understand pair production in PET imaging
  • Apply knowledge to optimize imaging and minimize dose

Photoelectric Effect

The photoelectric effect occurs when a photon is completely absorbed by an inner-shell electron:

  • Energy requirement: Photon energy > binding energy of electron
  • Result: Ejection of photoelectron + characteristic X-rays
  • Probability: Proportional to Z³/E³
  • Clinical significance: Attenuation in dense tissues (bone), basis for contrast
Key Point: Photoelectric absorption is the dominant interaction at low energies (<100 keV) and in high-Z materials.

Compton Scattering

Compton scatter involves partial energy transfer between photon and outer-shell electron:

  • Energy range: 100 keV - 2 MeV (most nuclear medicine energies)
  • Result: Scattered photon + recoil electron
  • Impact on imaging: Degrades contrast and resolution
  • Minimization: Energy windows, scatter correction algorithms

Pair Production

Occurs when photon energy exceeds 1.022 MeV:

  • Only relevant for PET (511 keV is below threshold, but high-energy therapy nuclides)
  • Result: Electron-positron pair created
  • Location: Near nucleus to conserve momentum

Attenuation

Linear attenuation coefficient (μ) describes overall photon absorption:

I=I0eμxI = I_0 \cdot e^{-\mu x}

Half-Value Layer (HVL)

The thickness that reduces intensity by 50%:

HVL=0.693μHVL = \frac{0.693}{\mu}

Content under development: Attenuation correction, scatter correction algorithms